Schmitt, Charlotte C. Aranias, Thomas Viel, Thomas Chateau, Danielle Le Gall, Maude Waligora-Dupriet, Anne-Judith Melchior, Chloé Rouxel, Ophélie Kapel, Nathalie Gourcerol, Guillaume
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Published in
Molecular Metabolism
Objective
Intestinal glucose absorption is orchestrated by specialized glucose transporters such as SGLT1 and GLUT2. However, the role of GLUT2 in the regulation of glucose absorption remains to be fully elucidated.
Methods
We wanted to evaluate the role of GLUT2 on glucose absorption and glucose homeostasis after intestinal-specific deletion ...
Picard, Alexandre Rouch, Claude Kassis, Nadim Moullé, Valentine S. Croizier, Sophie Denis, Raphaël G. Castel, Julien Coant, Nicolas Davis, Kathryn Clegg, Deborah J.
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Published in
Molecular Metabolism
Brain lipid sensing is necessary to regulate energy balance. Lipoprotein lipase (LPL) may play a role in this process. We tested if hippocampal LPL regulated energy homeostasis in rodents by specifically attenuating LPL activity in the hippocampus of rats and mice, either by infusing a pharmacological inhibitor (tyloxapol), or using a genetic appro...
