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Recombinant overexpression of camel hepcidin cDNA in Pichia pastoris: purification and characterization of the polyHis-t...

Mohamed Boumaiza Chahed, Haifa Ezzine, Aymen Jaouan, Maryse Gianoncelli, Alessandra Longhi, Giovanna Carmona, Fernando Arosio, Paolo Marie-Agnès Sari Marzouki, Mohamed Nejib ...

Published in Journal of Molecular Recognition

Hepcidin, a liver‐expressed antimicrobial peptide, has been demonstrated to act as an iron regulatory hormone as well as to exert a wide spectrum of antimicrobial activity. The aim of this work was the expression, as secreted peptide, purification, and characterization of a new recombinant polyHis‐tagged camel hepcidin (HepcD‐His) in yeast Pichia p...

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