Recherche de publications

Recombinant human activated protein C for adults with septic shock: a randomized controlled trial.

Published in Hepatology (Baltimore, Md.)

In adults with established and severe septic shock, DAA showed no evidence of benefit or harm. Clinical trial registered with www.clinicaltrials.gov (NCT00625209).

Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel funct...

Published in Hepatology (Baltimore, Md.)

These data provide a new mechanism and show for the first time a link between NE-calpains activation and CFTR loss of function in bacterial lung infections relevant to CF and to other chronic inflammatory lung conditions.

Continuation of amiodarone therapy despite type II amiodarone-induced thyrotoxicosis.

Published in Am J Respir Crit Care Med

In patients who require amiodarone, treatment may be safely continued despite the development of type II amiodarone-induced thyrotoxicosis.

Assessment of the interplay between blood and skin vascular abnormalities in adult purpura fulminans.

Published in Hepatology (Baltimore, Md.)

Thrombi and extensive vascular damage with multifaceted prothrombotic local imbalance are characteristics of purpura fulminans. A "vascular wall infection" hypothesis, responsible for endothelial damage and subsequent skin lesions, can be put forward.

Reviewing 741 patients records in two hours with FASTVISU

Published in Am J Respir Crit Care Med

Prenatal and postnatal presentations of corpus callosum agenesis with polymicrogyria caused by EGP5 mutation

Published in Am J Respir Crit Care Med

Does data rounding-off influence reproducibility index estimates?

Published in Am J Respir Crit Care Med

The intraclass correlation coefficient (ICC) is the reproducibility index commonly used to assess the reproducibility level of continuous data. Such data are collected with finite precision (i.e., a finite number of decimal digits corresponding to the level of data rounding-off error). We therefore investigated the consequences of having finite pre...

Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Proj...

Published in Am J Respir Crit Care Med

This consensus document provides an update for pathologists and clinicians about the interpretation of biopsy results and use of this information in the management of hematopoietic cell transplantation patients. Optimal sampling and tissue preparation are discussed. Minimal criteria for the diagnosis of graft-versus-host disease (GVHD) are proposed...

A novel missense mutation in the gene EDARADD associated with an unusual phenotype of hypohidrotic ectodermal dysplasia

Published in Am J Respir Crit Care Med

Adverse events associated with rofecoxib therapy: results of a large study in community-derived osteoarthritic patients....

Published in Am J Respir Crit Care Med

This study conducted in conditions close to daily practice confirms that the use of rofecoxib is associated with a low rate of serious adverse events in patients with osteoarthritis.