Howard, GeorgeRoubin, Gary SJansen, OlavHendrikse, JeroenHalliday, AlisonFraedrich, GustavEckstein, Hans-HenningCalvet, DavidBulbulia, RichardBonati, Leo H
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South, Sarah TAugustine, Nancy HBush, Jeana SDolen, William KWray, Betty BItan, YuvalCobat, AurelieSorte, Hanne SørmoGanesan, SundarPrader, Seraina
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BACKGROUND: Common variable immunodeficiency (CVID) is characterized by late-onset hypogammaglobulinemia in the absence of predisposing factors. The genetic cause is unknown in the majority of cases, and less than 10% of patients have a family history of the disease. Most patients have normal numbers of B cells but lack plasma cells. METHODS: We us...